ER+, LNN, adjuvant tamoxifen
The purpose of this study was to assess the benefit from adjuvant systemic tamoxifen therapy in breast cancer risk groups identified by the previously established prognostic 76-gene signature.
The hypothesis of this study is that the 76-gene signature can predict survival and benefit from adjuvant endocrine therapy in LNN ER-positive patients who received adjuvant systemic therapy with tamoxifen alone.
This dataset consists of a cohort of 136 breast cancer patients treated with adjuvant tamoxifen. Frozen tumor specimens were selected from the tumor banks in three of the four European institutions that provided the samples of patients without systemic therapy, i.e., Institute of Oncology, Ljubljana, Slovenia (36 samples; 1997–1999), National Cancer Institute, Bari, Italy (28 samples; 1990–1998), and Technische Universitaet Muenchen, Germany (9 samples; 1992–1999), and from one US institution, Cleveland Clinic Foundation (63 samples; 1981–2000). The distant metastasis-free survival (DMFS) among patients from different institutions was not different (log rank P = 0.63). All samples were drawn from the consecutive series of patients available in the institutions within the respective periods based on pre-defined inclusion criteria: histological diagnosis of LNN breast cancer, ER-positive primary tumor, adjuvant tamoxifen treatment, informed consent and/or approval by a local Ethical Committee, at least 5 years of follow-up except for patients who developed distant relapse within 5 years, no signs of disease within 1 month after primary surgery, and frozen tissue should be available. Exclusion criteria were: neoadjuvant or adjuvant chemotherapy, history of other primary cancer (except for basal cell carcinoma), less than 50% tumor area on hematoxylin/eosin (HE) section at time of extraction of RNA, or poor RNA quality.
--
--
Total RNA was extracted from tumor tissues (median 90 mg; range 40–120 mg) at the Erasmus MC, Rotterdam, as described by Wang et al and at Cleveland Clinic Foundation, Cleveland, and was sent to Veridex LLC, San Diego, for further analysis. The median RNA yield was 82 ?g (range 19–240 ?g). RNA quality was checked by use of the Agilent BioAnalyzer, and samples were profiled only if they had clear distinct 18S and 28S peaks with no minor peaks present, the area under the 18S and 28S peaks was more than 15% of the total RNA area, and if the 28S/18S ratio was between 1.2 and 2.0. Biotinylated targets were prepared using published methods (Affymetrix, CA) and hybridized to Affymetrix U133A GeneChips (Affymetrix, CA). Chips with average intensity of less than 40 or background signal of more than 100 were excluded. Each probe set was considered as a separate gene. Expression values for each gene were calculated using Affymetrix GeneChip analysis software MAS 5.0. For scaling, probe sets were scaled to a target intensity of 600 and scale mask filters were not selected.
The microarray data were nonlinearly normalized, using a cubic B-spline smoother, to ensure the same signal intensity distribution as the original discovery dataset used to establish the 76-gene signature (Wang et al).
Zhang, Yi, Anieta M. Sieuwerts, Michelle McGreevy, Graham Casey, Tanja Cufer, Angelo Paradiso, Nadia Harbeck, et al. “The 76-Gene Signature Defines High-Risk Patients That Benefit from Adjuvant Tamoxifen Therapy.” Breast Cancer Research and Treatment 116, no. 2 (July 2009): 303–9. doi:10.1007/s10549-008-0183-2.
Wang, Yixin, Jan G. M. Klijn, Yi Zhang, Anieta M. Sieuwerts, Maxime P. Look, Fei Yang, Dmitri Talantov, et al. “Gene-Expression Profiles to Predict Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer.” Lancet (London, England) 365, no. 9460 (February 19, 2005): 671–79. doi:10.1016/S0140-6736(05)17947-1.
Sample ID | series | IMS | IBS | IDS | ICR |
---|---|---|---|---|---|
GSM305129 | NA | Basal | IBE | PID | ICR2 |
GSM305130 | NA | LumA | IBD | PID | ICR2 |
GSM305131 | NA | Basal | IBE | WID | ICR4 |
GSM305132 | NA | LumB | IBE | FID | ICR4 |
GSM305133 | NA | Her2 | IBD | PID | ICR1 |
All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.
Sample ID | Series | IMS | IBS | IDS | ICR | Array Sample ID | Sample Title | DMFS 10Y EVENT | DMFS 10Y TIME | Disease Free Survival Event | Distant Met Free Survival Event | Distant Met Free Survival | Age At Initial Pathologic Diagnosis | Lymph Node Status | ER Status | PR Status | Histology Differentiation Grade | Tumor Size Cm | Pathology T Stage | Disease Free Survival Days |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GSM305129 | NA |
Basal |
IBE |
PID |
ICR2 |
400002656 |
breast tumor sample 3001 |
DistantMetastasisFree |
5 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
60 |
GSM305130 | NA |
LumA |
IBD |
PID |
ICR2 |
400002657 |
breast tumor sample 3002 |
DistantMetastasisFree |
5.72 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
686 |
GSM305131 | NA |
Basal |
IBE |
WID |
ICR4 |
400002658 |
breast tumor sample 3003 |
DistantMetastasisFree |
5.28 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
633 |
GSM305132 | NA |
LumB |
IBE |
FID |
ICR4 |
400002659 |
breast tumor sample 3004 |
DistantMetastasisFree |
5.11 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
613 |
GSM305133 | NA |
Her2 |
IBD |
PID |
ICR1 |
400002660 |
breast tumor sample 3005 |
DistantMetastasisFree |
5.58 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
669 |
GSM305134 | NA |
LumB |
IBD |
PID |
ICR2 |
400002661 |
breast tumor sample 3006 |
DistantMetastasisFree |
5.26 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
631 |
GSM305135 | NA |
LumB |
IBE |
PID |
ICR1 |
400002662 |
breast tumor sample 3007 |
DistantMetastasis |
5.05 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
606 |
GSM305136 | NA |
LumA |
IBD |
PID |
ICR1 |
400002663 |
breast tumor sample 3009 |
DistantMetastasisFree |
5.29 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
635 |
GSM305137 | NA |
Her2 |
IBD |
PID |
ICR2 |
400002664 |
breast tumor sample 3012 |
DistantMetastasisFree |
5.35 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
642 |
GSM305138 | NA |
Normal |
IBE |
NA |
ICR3 |
400002665 |
breast tumor sample 3013 |
DistantMetastasisFree |
5.15 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
618 |
GSM305139 | NA |
NA |
IBE |
NA |
ICR2 |
400002666 |
breast tumor sample 3014 |
DistantMetastasisFree |
5 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
60 |
GSM305140 | NA |
Her2 |
IBD |
WID |
ICR3 |
400002667 |
breast tumor sample 3015 |
DistantMetastasis |
3.72 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
446 |
GSM305141 | NA |
Her2 |
IBD |
PID |
ICR1 |
400002668 |
breast tumor sample 3329 |
DistantMetastasisFree |
5.28 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
633 |
GSM305142 | NA |
Normal |
IBE |
NA |
ICR2 |
400002669 |
breast tumor sample 3331 |
DistantMetastasisFree |
5.68 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
681 |
GSM305143 | NA |
LumA |
IBD |
PID |
ICR1 |
400002670 |
breast tumor sample 3333 |
DistantMetastasisFree |
5.66 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
679 |
GSM305144 | NA |
Basal |
IBE |
WID |
ICR3 |
400002671 |
breast tumor sample 3335 |
DistantMetastasisFree |
6.75 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
81 |
GSM305145 | NA |
LumB |
IBD |
PID |
ICR1 |
400002672 |
breast tumor sample 3336 |
DistantMetastasisFree |
6.9 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
828 |
GSM305146 | NA |
LumB |
IBE |
FID |
ICR4 |
400002673 |
breast tumor sample 3337 |
DistantMetastasisFree |
5.49 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
659 |
GSM305147 | NA |
LumA |
IBD |
PID |
ICR3 |
400002674 |
breast tumor sample 3338 |
DistantMetastasisFree |
6.58 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
79 |
GSM305148 | NA |
NA |
IBE |
NA |
ICR1 |
400002675 |
breast tumor sample 3340 |
DistantMetastasisFree |
5.13 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
616 |
GSM305149 | NA |
Normal |
IBE |
NA |
ICR3 |
400002676 |
breast tumor sample 3343 |
DistantMetastasisFree |
7.02 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
842 |
GSM305150 | NA |
LumA |
IBD |
PID |
ICR2 |
400002677 |
breast tumor sample 3250 |
DistantMetastasisFree |
9.16 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1099 |
GSM305151 | NA |
LumB |
IBD |
WID |
ICR3 |
400002678 |
breast tumor sample 3251 |
DistantMetastasis |
5.41 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
649 |
GSM305152 | NA |
Basal |
IBE |
WID |
ICR3 |
400002679 |
breast tumor sample 3252 |
DistantMetastasisFree |
5.6 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
672 |
GSM305153 | NA |
Her2 |
IBE |
PID |
ICR3 |
400002680 |
breast tumor sample 3253 |
DistantMetastasis |
1.91 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
229 |
GSM305154 | NA |
LumA |
IBD |
PID |
ICR1 |
400002681 |
breast tumor sample 3254 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1246 |
GSM305155 | NA |
Normal |
IBE |
NA |
ICR3 |
400002682 |
breast tumor sample 3256 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1229 |
GSM305156 | NA |
Basal |
IBE |
PID |
ICR3 |
400002683 |
breast tumor sample 3257 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1214 |
GSM305157 | NA |
Basal |
IBE |
WID |
ICR4 |
400002684 |
breast tumor sample 3258 |
DistantMetastasis |
0.63 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
76 |
GSM305158 | NA |
LumA |
IBD |
PID |
ICR2 |
400002685 |
breast tumor sample 3259 |
DistantMetastasisFree |
9.97 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1196 |
GSM305159 | NA |
LumA |
IBD |
WID |
ICR2 |
400002686 |
breast tumor sample 3260 |
DistantMetastasisFree |
9.86 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1183 |
GSM305160 | NA |
LumB |
IBD |
PID |
ICR2 |
400002687 |
breast tumor sample 3261 |
DistantMetastasisFree |
5.18 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
621 |
GSM305161 | NA |
Her2 |
IBD |
WID |
ICR2 |
400002688 |
breast tumor sample 3262 |
DistantMetastasisFree |
9.71 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1165 |
GSM305162 | NA |
Her2 |
IBE |
FID |
ICR4 |
400002689 |
breast tumor sample 3263 |
DistantMetastasisFree |
5.16 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
619 |
GSM305163 | NA |
LumA |
IBD |
PID |
ICR1 |
400002690 |
breast tumor sample 3265 |
DistantMetastasisFree |
8.24 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
989 |
GSM305164 | NA |
LumB |
IBE |
PID |
ICR3 |
400002691 |
breast tumor sample 3266 |
DistantMetastasis |
3 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
36 |
GSM305165 | NA |
LumB |
IBD |
PID |
ICR1 |
400002692 |
breast tumor sample 3267 |
DistantMetastasisFree |
6.72 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
806 |
GSM305166 | NA |
Basal |
IBE |
WID |
ICR3 |
400002693 |
breast tumor sample 3269 |
DistantMetastasisFree |
8.43 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1012 |
GSM305167 | NA |
LumA |
IBD |
PID |
ICR1 |
400002694 |
breast tumor sample 3270 |
DistantMetastasisFree |
6.43 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
772 |
GSM305168 | NA |
Her2 |
IBD |
PID |
ICR2 |
400002695 |
breast tumor sample 3271 |
DistantMetastasisFree |
5.35 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
642 |
GSM305169 | NA |
Basal |
IBE |
PID |
ICR1 |
400002696 |
breast tumor sample 3272 |
DistantMetastasisFree |
9.71 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1165 |
GSM305170 | NA |
LumA |
IBD |
PID |
ICR3 |
400002697 |
breast tumor sample 3273 |
DistantMetastasisFree |
9.18 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1101 |
GSM305171 | NA |
LumB |
IBD |
PID |
ICR2 |
400002698 |
breast tumor sample 3274 |
DistantMetastasisFree |
9.15 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1098 |
GSM305172 | NA |
LumB |
IBE |
WID |
ICR3 |
400002699 |
breast tumor sample 3275 |
DistantMetastasis |
6.33 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
759 |
GSM305173 | NA |
Her2 |
IBE |
PID |
ICR3 |
400002700 |
breast tumor sample 3276 |
DistantMetastasisFree |
7.9 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
948 |
GSM305174 | NA |
Basal |
IBE |
FID |
ICR4 |
400002701 |
breast tumor sample 3277 |
DistantMetastasisFree |
7.6 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
912 |
GSM305175 | NA |
LumB |
IBE |
PID |
ICR1 |
400002702 |
breast tumor sample 3278 |
DistantMetastasisFree |
6.95 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
834 |
GSM305176 | NA |
LumA |
IBD |
PID |
ICR1 |
400002703 |
breast tumor sample 3279 |
DistantMetastasisFree |
7.26 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
871 |
GSM305177 | NA |
Basal |
IBE |
FID |
ICR4 |
400002704 |
breast tumor sample 3280 |
DistantMetastasisFree |
7.13 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
856 |
GSM305178 | NA |
Normal |
IBE |
NA |
ICR2 |
400002705 |
breast tumor sample 100 |
DistantMetastasisFree |
9.47 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1136 |
GSM305179 | NA |
LumA |
IBD |
WID |
ICR2 |
400002706 |
breast tumor sample 108 |
DistantMetastasisFree |
9.07 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1088 |
GSM305180 | NA |
LumA |
IBD |
WID |
ICR2 |
400002707 |
breast tumor sample 123 |
DistantMetastasis |
2.45 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
294 |
GSM305181 | NA |
Basal |
IBE |
FID |
ICR3 |
400002708 |
breast tumor sample 128 |
DistantMetastasisFree |
8.59 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1031 |
GSM305182 | NA |
Basal |
IBE |
FID |
ICR4 |
400002709 |
breast tumor sample 129 |
DistantMetastasisFree |
8.53 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1023 |
GSM305183 | NA |
LumB |
IBD |
PID |
ICR2 |
400002710 |
breast tumor sample 57 |
DistantMetastasisFree |
7.74 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
929 |
GSM305184 | NA |
Normal |
IBE |
NA |
ICR3 |
400002711 |
breast tumor sample 65 |
DistantMetastasisFree |
8.68 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1041 |
GSM305185 | NA |
LumA |
IBD |
PID |
ICR1 |
400002712 |
breast tumor sample 71 |
DistantMetastasisFree |
8.21 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
985 |
GSM305186 | NA |
Normal |
IBE |
NA |
ICR3 |
400002713 |
breast tumor sample 172 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1389 |
GSM305187 | NA |
Basal |
IBE |
FID |
ICR4 |
400002714 |
breast tumor sample 175 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1283 |
GSM305188 | NA |
Normal |
IBE |
NA |
ICR3 |
400002715 |
breast tumor sample 9253 |
DistantMetastasisFree |
9.1 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1092 |
GSM305189 | NA |
Normal |
IBE |
NA |
ICR2 |
400002716 |
breast tumor sample 9442 |
DistantMetastasisFree |
9.51 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1141 |
GSM305190 | NA |
Normal |
IBE |
NA |
ICR3 |
400002717 |
breast tumor sample 2143 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
154 |
GSM305191 | NA |
Normal |
IBE |
NA |
ICR2 |
400002718 |
breast tumor sample 2162 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1489 |
GSM305192 | NA |
LumB |
IBE |
PID |
ICR3 |
400002719 |
breast tumor sample 2048 |
DistantMetastasis |
2.43 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
291 |
GSM305193 | NA |
ClaudinLow |
IBD |
FID |
ICR4 |
400002720 |
breast tumor sample 2534 |
DistantMetastasisFree |
6.52 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
782 |
GSM305194 | NA |
LumB |
IBD |
PID |
ICR1 |
400002721 |
breast tumor sample 2536 |
DistantMetastasis |
8.68 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1041 |
GSM305195 | NA |
Normal |
IBE |
NA |
ICR3 |
400002722 |
breast tumor sample 2556 |
DistantMetastasisFree |
5.21 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
625 |
GSM305196 | NA |
LumA |
IBD |
WID |
ICR2 |
400002723 |
breast tumor sample 2588 |
DistantMetastasisFree |
6.35 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
762 |
GSM305197 | NA |
LumA |
IBD |
FID |
ICR3 |
400002724 |
breast tumor sample 2647 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1926 |
GSM305198 | NA |
NA |
IBE |
NA |
ICR4 |
400002725 |
breast tumor sample 2494 |
DistantMetastasis |
9.05 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1086 |
GSM305199 | NA |
NA |
IBE |
NA |
ICR3 |
400002726 |
breast tumor sample 2733 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1919 |
GSM305200 | NA |
LumB |
IBD |
PID |
ICR1 |
400002727 |
breast tumor sample 2639 |
DistantMetastasisFree |
10 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1395 |
GSM305201 | NA |
NA |
IBE |
NA |
ICR3 |
400002728 |
breast tumor sample 2872 |
DistantMetastasisFree |
5.18 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
622 |
GSM305202 | NA |
LumA |
IBD |
WID |
ICR2 |
400002729 |
breast tumor sample 2236 |
DistantMetastasisFree |
9 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
108 |
GSM305203 | NA |
Basal |
IBE |
PID |
ICR2 |
400002730 |
breast tumor sample 2308 |
DistantMetastasisFree |
10 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1643 |
GSM305204 | NA |
Basal |
IBE |
WID |
ICR3 |
400002731 |
breast tumor sample 41826 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
151 |
GSM305205 | NA |
Normal |
IBE |
NA |
ICR2 |
400002732 |
breast tumor sample 21514 |
DistantMetastasisFree |
8.15 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
978 |
GSM305206 | NA |
Normal |
IBE |
NA |
ICR2 |
400002733 |
breast tumor sample 21590 |
DistantMetastasisFree |
5.94 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
713 |
GSM305207 | NA |
LumA |
IBD |
PID |
ICR1 |
400002734 |
breast tumor sample 21604 |
DistantMetastasis |
3.95 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
474 |
GSM305208 | NA |
Normal |
IBE |
NA |
ICR2 |
400002735 |
breast tumor sample 21572 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1297 |
GSM305209 | NA |
Her2 |
IBE |
PID |
ICR1 |
400002736 |
breast tumor sample 9191 |
DistantMetastasisFree |
9.68 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1162 |
GSM305210 | NA |
LumB |
IBD |
WID |
ICR2 |
400002737 |
breast tumor sample 21815 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1304 |
GSM305211 | NA |
LumA |
IBD |
PID |
ICR1 |
400002738 |
breast tumor sample 21790 |
DistantMetastasis |
5.77 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
692 |
GSM305212 | NA |
LumA |
IBD |
PID |
ICR1 |
400002739 |
breast tumor sample 21148 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1913 |
GSM305213 | NA |
Normal |
IBE |
NA |
ICR3 |
400002740 |
breast tumor sample 2492 |
DistantMetastasisFree |
5.01 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
601 |
GSM305214 | NA |
Normal |
IBE |
NA |
ICR2 |
400002741 |
breast tumor sample 2056 |
DistantMetastasisFree |
5.1 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
612 |
GSM305215 | NA |
Normal |
IBE |
NA |
ICR1 |
400002742 |
breast tumor sample 2548 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1773 |
GSM305216 | NA |
Her2 |
IBE |
PID |
ICR2 |
400002743 |
breast tumor sample 21279 |
DistantMetastasis |
3.18 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
382 |
GSM305217 | NA |
LumB |
IBE |
PID |
ICR1 |
400002744 |
breast tumor sample 21276 |
DistantMetastasis |
2.58 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
309 |
GSM305218 | NA |
Basal |
IBE |
WID |
ICR3 |
400002745 |
breast tumor sample 2342 |
DistantMetastasisFree |
5.16 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
619 |
GSM305219 | NA |
Normal |
IBE |
NA |
ICR2 |
400002746 |
breast tumor sample 2455 |
DistantMetastasisFree |
7.65 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
918 |
GSM305220 | NA |
Normal |
IBE |
NA |
ICR2 |
400002747 |
breast tumor sample 2354 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1608 |
GSM305221 | NA |
Normal |
IBE |
NA |
ICR2 |
400002748 |
breast tumor sample 2386 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1323 |
GSM305222 | NA |
LumA |
IBD |
PID |
ICR1 |
400002749 |
breast tumor sample 2420 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1628 |
GSM305223 | NA |
LumA |
IBD |
WID |
ICR1 |
400002750 |
breast tumor sample 2237 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1416 |
GSM305224 | NA |
LumB |
IBD |
WID |
ICR3 |
400002751 |
breast tumor sample 2297 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1356 |
GSM305225 | NA |
LumB |
IBD |
WID |
ICR3 |
400002752 |
breast tumor sample 2392 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1821 |
GSM305226 | NA |
Normal |
IBE |
NA |
ICR2 |
400002753 |
breast tumor sample 2377 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1763 |
GSM305227 | NA |
LumA |
IBD |
WID |
ICR2 |
400002754 |
breast tumor sample 8 |
DistantMetastasisFree |
8.8 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1056 |
GSM305228 | NA |
Normal |
IBE |
NA |
ICR2 |
400002755 |
breast tumor sample 19 |
DistantMetastasisFree |
9.4 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1128 |
GSM305229 | NA |
Normal |
IBE |
NA |
ICR3 |
400002756 |
breast tumor sample 33 |
DistantMetastasisFree |
8.06 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
967 |
GSM305230 | NA |
Normal |
IBE |
NA |
ICR2 |
400002757 |
breast tumor sample 37 |
DistantMetastasisFree |
8.61 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1033 |
GSM305231 | NA |
LumB |
IBD |
PID |
ICR2 |
400002758 |
breast tumor sample 38 |
DistantMetastasisFree |
8.34 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1001 |
GSM305232 | NA |
Basal |
IBE |
WID |
ICR3 |
400002759 |
breast tumor sample 46 |
DistantMetastasisFree |
5.26 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
631 |
GSM305233 | NA |
LumA |
IBD |
PID |
ICR1 |
400002760 |
breast tumor sample 87 |
DistantMetastasisFree |
9.69 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1163 |
GSM305234 | NA |
LumA |
IBD |
FID |
ICR4 |
400002761 |
breast tumor sample 88 |
DistantMetastasisFree |
8.39 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1007 |
GSM305235 | NA |
Normal |
IBE |
NA |
ICR2 |
400002762 |
breast tumor sample 92 |
DistantMetastasisFree |
8.67 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
104 |
GSM305236 | NA |
Basal |
IBE |
WID |
ICR2 |
400002763 |
breast tumor sample 2160 |
DistantMetastasis |
1.1 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
132 |
GSM305237 | NA |
Normal |
IBE |
NA |
ICR2 |
400002764 |
breast tumor sample 2309 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1635 |
GSM305238 | NA |
LumB |
IBE |
WID |
ICR3 |
400002765 |
breast tumor sample 3344 |
DistantMetastasisFree |
6.88 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
825 |
GSM305239 | NA |
LumA |
IBD |
WID |
ICR3 |
400002766 |
breast tumor sample 3346 |
DistantMetastasisFree |
5.07 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
608 |
GSM305240 | NA |
Her2 |
IBE |
PID |
ICR3 |
400002767 |
breast tumor sample 3347 |
DistantMetastasisFree |
7.47 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
896 |
GSM305241 | NA |
LumA |
IBD |
PID |
ICR2 |
400002768 |
breast tumor sample 3348 |
DistantMetastasisFree |
6.95 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
834 |
GSM305242 | NA |
LumB |
IBE |
PID |
ICR1 |
400002769 |
breast tumor sample 3349 |
DistantMetastasisFree |
7.78 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
934 |
GSM305243 | NA |
Basal |
IBE |
WID |
ICR4 |
400002770 |
breast tumor sample 3350 |
DistantMetastasis |
1.25 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
15 |
GSM305244 | NA |
LumB |
IBD |
PID |
ICR1 |
400002771 |
breast tumor sample 3351 |
DistantMetastasisFree |
5.22 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
626 |
GSM305245 | NA |
LumB |
IBE |
PID |
ICR1 |
400002772 |
breast tumor sample 3352 |
DistantMetastasisFree |
6.96 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
835 |
GSM305246 | NA |
Basal |
IBE |
PID |
ICR2 |
400002773 |
breast tumor sample 3353 |
DistantMetastasisFree |
6.99 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
839 |
GSM305247 | NA |
Her2 |
IBD |
PID |
ICR2 |
400002774 |
breast tumor sample 3354 |
DistantMetastasisFree |
6.88 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
825 |
GSM305248 | NA |
Basal |
IBE |
FID |
ICR4 |
400002775 |
breast tumor sample 3355 |
DistantMetastasisFree |
7.52 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
902 |
GSM305249 | NA |
LumB |
IBD |
PID |
ICR1 |
400002776 |
breast tumor sample 3356 |
DistantMetastasisFree |
6.62 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
794 |
GSM305250 | NA |
LumA |
IBD |
WID |
ICR2 |
400002777 |
breast tumor sample 3357 |
DistantMetastasisFree |
5.16 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
619 |
GSM305251 | NA |
LumB |
IBD |
PID |
ICR1 |
400002778 |
breast tumor sample 3360 |
DistantMetastasisFree |
6.21 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
745 |
GSM305252 | NA |
LumB |
IBE |
WID |
ICR3 |
400002779 |
breast tumor sample 3362 |
DistantMetastasisFree |
5.26 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
631 |
GSM305253 | NA |
LumB |
IBE |
WID |
ICR3 |
400002780 |
breast tumor sample 3363 |
DistantMetastasisFree |
7.02 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
842 |
GSM305254 | NA |
LumB |
IBE |
PID |
ICR3 |
400002781 |
breast tumor sample 3364 |
DistantMetastasisFree |
7.55 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
906 |
GSM305255 | NA |
LumB |
IBE |
WID |
ICR3 |
400002782 |
breast tumor sample 3365 |
DistantMetastasisFree |
5.64 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
677 |
GSM305256 | NA |
LumB |
IBE |
FID |
ICR4 |
400002783 |
breast tumor sample 3366 |
DistantMetastasisFree |
6.31 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
757 |
GSM305257 | NA |
LumB |
IBE |
PID |
ICR1 |
400002784 |
breast tumor sample 3367 |
DistantMetastasisFree |
6.76 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
811 |
GSM305258 | NA |
LumB |
IBE |
PID |
ICR1 |
400002785 |
breast tumor sample 3368 |
DistantMetastasisFree |
7.35 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
882 |
GSM305259 | NA |
Basal |
IBE |
FID |
ICR4 |
400002786 |
breast tumor sample 3369 |
DistantMetastasisFree |
7.38 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
885 |
GSM305260 | NA |
LumA |
IBD |
PID |
ICR1 |
400002787 |
breast tumor sample 3370 |
DistantMetastasisFree |
7.03 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
843 |
GSM305261 | NA |
Her2 |
IBD |
PID |
ICR2 |
400002788 |
breast tumor sample 3371 |
DistantMetastasisFree |
6.97 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
836 |
GSM305262 | NA |
Basal |
IBE |
PID |
ICR2 |
400002789 |
breast tumor sample 9 |
DistantMetastasisFree |
8.89 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1067 |
GSM305263 | NA |
Basal |
IBE |
PID |
ICR2 |
400002790 |
breast tumor sample 42 |
DistantMetastasis |
2.47 |
Progressed/Recurred |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
296 |
GSM305264 | NA |
Normal |
IBE |
NA |
ICR2 |
400002791 |
breast tumor sample 77 |
DistantMetastasisFree |
10 |
DiseaseFree |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
1796 |
Name | ||
---|---|---|
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